abstract：BACKGROUND:Cisplatin is used as a key drug for ovarian yolk sac tumor (YST), but relapse may occur. Details of the molecular mechanism responsible for cisplatin resistance remain unclear. METHODS:We established cisplatin-resistant ovarian YST cells (NOY1-CR) from parent NOY1. To characterize these cells, we examined c...

journal_title：Gynecologic and obstetric investigation

authors： Shibata K,Umezu T,Sakurai M,Kajiyama H,Yamamoto E,Ino K,Nawa A,Kikkawa F

更新日期：2011-01-01 00:00:00

abstract：AIMS:The purpose was to investigate the influence of delivery mode on the postpartum regression of abnormal cervical cytology. METHODS:A retrospective review was conducted of 64 pregnant women with abnormal cervical cytology at Yonsei University Health System in Korea between 2001 and 2008. A Papanicolaou smear and pa...

journal_title：Gynecologic and obstetric investigation

authors： Chung SM,Son GH,Nam EJ,Kim YH,Kim YT,Park YW,Kwon JY

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND/AIMS:It has been reported that lower urinary tract symptoms (LUTS) are more prevalent in patients who have undergone hysterectomy. However, the effects of surgical approach of hysterectomy on micturition have not been well documented. The aim of this study is to compare LUTS between patients who underwent va...

journal_title：Gynecologic and obstetric investigation

authors： Lakeman MM,van der Vaart CH,Roovers JP,HysVA study group.

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Group B streptococcus (GBS) is an important cause of neonatal sepsis. Guidelines advise to collect cultures at 35-37 weeks' gestation and to administer intrapartum antibiotic prophylaxis in case of GBS-positive cultures, as well as in all preterm deliveries. Improved effectiveness of antenatal cultures might...

journal_title：Gynecologic and obstetric investigation

authors： Valkenburg-van den Berg AW,Houtman-Roelofsen RL,Oostvogel PM,Dekker FW,Dörr PJ,Sprij AJ

更新日期：2010-01-01 00:00:00

abstract：:We present a case of leiomyomatosis peritonealis disseminata (LPD) after myoma morcellation and review the literature using the keywords leiomyomatosis peritonealis disseminata and disseminated peritoneal leiomyomatosis. The search was conducted in Medline, EMBASE, and Cochrane Database of systematic reviews. We encou...

journal_title：Gynecologic and obstetric investigation

authors： Al-Talib A,Tulandi T

更新日期：2010-01-01 00:00:00

abstract：:We present a case study of a patient with a congenital heart block associated with a left isomerism that was diagnosed during the 26th week of gestation. The mother had type 2 diabetes mellitus that was difficult to control during the early stages of the pregnancy. A fetal echocardiogram revealed an atrioventricular d...

journal_title：Gynecologic and obstetric investigation

authors： Serikawa T,Ichikawa K,Kikuchi A,Takakuwa K,Tanaka K

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:Urinary bladder endometriosis is a severe form of endometriosis often requiring surgery. The several cases treated at our hospital in recent years has led us to evaluate the incidence of urinary bladder endometriosis in Finland. METHODS:We performed a register-based analysis of incidence of urinary bladder e...

journal_title：Gynecologic and obstetric investigation

authors： Vaarala MH,Hellstrom P,Santala M

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Dyslipidemia is commonly observed in polycystic ovary syndrome (PCOS) patients. Bezafibrate is a drug for dyslipidemia acting through peroxisome proliferator-activated receptors. We investigated the effects of bezafibrate for ovulation induction in patients with PCOS with dyslipidemia who were resistant to c...

journal_title：Gynecologic and obstetric investigation

authors： Hara S,Takahashi T,Amita M,Igarashi H,Kurachi H

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Little is known about proper interval periods between the flushings of totally implantable access ports after completion of chemotherapy. Manufacturer guidelines recommend flushing catheters every 4 weeks. METHODS:This retrospective study examined whether flushing less than every 4 weeks conferred any benef...

journal_title：Gynecologic and obstetric investigation

authors： Ignatov A,Ignatov T,Taran A,Smith B,Costa SD,Bischoff J

更新日期：2010-01-01 00:00:00

abstract：AIMS:To document progress with human papillomavirus (HPV) vaccine introduction in three closely related European countries, one with organized (the Netherlands) and two with opportunistic cervical cancer screening (Belgium and Luxembourg). METHODS:Experts involved in cervical cancer screening and national immunization...

journal_title：Gynecologic and obstetric investigation

authors： Arbyn M,Simoens C,Van Damme P,Scharpantgen A,Meijer CJ,Beutels P

更新日期：2010-01-01 00:00:00

abstract：INTRODUCTION:Maternal risk factors may interfere with mechanisms regulating fetal growth. The aim of the present study was to determine which sociodemographic and reproductive risk factors may be related to fetal growth restriction (FGR), with a special focus on determinants possible for preventive intervention. MATER...

journal_title：Gynecologic and obstetric investigation

authors： Vedmedovska N,Rezeberga D,Teibe U,Zodzika J,Donders GG

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND/AIMS:To evaluate the degree of pain during and after office hysteroscopy with combined intracervical and intrauterine anesthesia compared to intracervical anesthesia only. METHODS:We evaluated the amount of pain experienced during office hysteroscopy using combined local intracervical and intrauterine anest...

journal_title：Gynecologic and obstetric investigation

authors： Agdi M,Tulandi T

更新日期：2010-01-01 00:00:00

abstract：AIMS:To construct in vitro models of normal uterine arterial vascular network through vascular corrosion casting and explore their characteristics and clinical significances. METHODS:Three sets of uterus, vagina and bilateral adnexa were perfused and cast via uterine artery and ovarian artery, using 25, 20 and 15% chl...

journal_title：Gynecologic and obstetric investigation

authors： Chen C,Huang R,Liu P,Ouyang Z,Guo H,Tang L,Li Z,Liu C,Wu K,Zhong G,Hong H,Hu J,Li J,Zhong S

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND/AIMS:Pregnancy complicated by diabetes is associated with increased risk of unfavorable obstetric outcomes. A common abnormality in diabetes is endothelial dysfunction resulting in an altered pattern of vasoactive substance production by the endothelial cells. The aim of study was to assess serum endothelin-...

journal_title：Gynecologic and obstetric investigation

authors： Swiderski S,Celewicz Z,Miazgowski T,Ogonowski J

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND/AIMS:To determine whether genetic alterations in the CD9 gene are associated with female infertility in humans. METHODS:We sequenced the entire coding region of this gene in 86 Japanese women with unexplained infertility and further conducted a case-control study of six tagging single nucleotide polymorphis...

journal_title：Gynecologic and obstetric investigation

authors： Nishiyama S,Kishi T,Kato T,Suzuki M,Nishizawa H,Pryor-Koishi K,Sawada T,Nishiyama Y,Iwata N,Udagawa Y,Kurahashi H

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND/AIMS:To evaluate maternal serum transformed alpha-fetoprotein (MSt-AFP) levels, a new molecular conformation of AFP was used in cases of threatened preterm labor (TPL). METHODS:Prospective case-control study. Maternal serum levels of classical AFP and transformed AFP (t-AFP) were compared between 2 groups m...

journal_title：Gynecologic and obstetric investigation

authors： González-Bugatto F,Bailén Mde L,Fernández-Macías R,Fernández-Deudero A,Hervías-Vivancos B,Bartha JL

更新日期：2009-01-01 00:00:00

abstract：:The long-term effects of valproic acid (VPA) on reproductive endocrine functions in women with epilepsy (WWE) were studied. Serum reproductive hormone concentrations, clinical findings and ovarian morphology were analyzed in 71 WWE who had been receiving antiepileptic drugs (AED) for a minimum of 2 years. Of the 71 WW...

journal_title：Gynecologic and obstetric investigation

authors： Gorkemli H,Genc BO,Dogan EA,Genc E,Ozdemir S

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Tuberculous paraplegia as a consequence of spinal infiltration in pregnancy is reported to be rare. Analysis of the current literature produces few case studies that report successful outcomes. Delay in diagnosis and treatment may ultimately result in an irreversible neurological deficit. The potential impli...

journal_title：Gynecologic and obstetric investigation

authors： Loughenbury P,Pavlou G,Dunsmuir R

更新日期：2009-01-01 00:00:00

abstract：:Guillain-Barré syndrome (GBS) is an acute or subacute demyelinating polyneuropathy that rarely complicates pregnancy, but increases maternal and perinatal morbidity. A 15-year-old pregnant woman was admitted with ascending paralysis and acellular lumbar puncture suggestive of GBS. She required mechanical ventilation f...

journal_title：Gynecologic and obstetric investigation

authors： Campos da Silva F,de Moraes Paula G,Dos Santos Esteves Automari CV,Mendes de Almeida DS,Ubirajara Cavalcanti Guimarães R

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND/AIMS:The aim of this meta-analysis was to determine whether frozen embryo transfer (ET) increases ectopic pregnancy (EP) rate compared with fresh ET. METHODS:A meta-analysis was performed of data from seven comparative studies including 13,059 pregnancies that resulted from nondonor in vitro fertilization c...

journal_title：Gynecologic and obstetric investigation

authors： Jee BC,Suh CS,Kim SH

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND/AIMS:The aim of our study was to evaluate the prevalence of abuse among pregnant women in Germany attending our antenatal outpatient clinic and to observe whether a history of abuse had consequences for women's feelings about their pregnancy. METHODS:455 women between the 35th and 42nd weeks of gestational ...

journal_title：Gynecologic and obstetric investigation

authors： Jundt K,Haertl K,Knobbe A,Kaestner R,Friese K,Peschers UM

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND/AIMS:Some embryo implantation problems in patients with recurrent implantation failure may be explained by the inability of the embryo to hatch out of its zona pellucida. In this case-control study, a study group which had received modified quarter laser-assisted zona thinning (mQLAZT) was compared with a co...

journal_title：Gynecologic and obstetric investigation

authors： Debrock S,Spiessens C,Peeraer K,De Loecker P,Willemen D,D'Hooghe TM

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVE:To compare the qualitative (QL) and quantitative (QN) levels of betahCG in cervicovaginal secretions as predictors of preterm birth. METHODS:The study included 100 women. QL and QN assays were done with velocit kit and ELISA, respectively. RESULTS:A positive QL assay had sensitivity of 78%, specificity 95%,...

journal_title：Gynecologic and obstetric investigation

authors： Rengaraj G,Guleria K,Suneja A,Gambhir JK

更新日期：2009-01-01 00:00:00

abstract：AIMS:To evaluate the efficacies of the estrogen receptor-alpha (ER-alpha) gene polymorphisms and of the intrafollicular insulin-like growth factor (IGF) system for predicting pregnancy in in vitro fertilization and embryo transfer (IVF-ET) patients. METHODS:A total of 96 patients undergoing IVF-ET were included in thi...

journal_title：Gynecologic and obstetric investigation

authors： Choi YS,Kim SH,Ku SY,Jee BC,Suh CS,Choi YM,Kim JG,Moon SY

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVE:Premature labor is still the leading cause of infant mortality and morbidity worldwide. Multiple etiological factors including genetics and environment are held responsible for preterm birth. However, scientific data regarding the link between premature birth and genetics are limited. SUBJECTS AND METHODS:In...

journal_title：Gynecologic and obstetric investigation

authors： Uvuz F,Kilic S,Yilmaz N,Tuncay G,Cakar E,Yuksel B,Bilge U

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND/AIMS:Limited information is available regarding the quantity of blood loss associated with uncomplicated transvaginal oocyte retrieval. The aim of the present study was evaluating the quantity of such a loss. METHODS:One hundred and fifty consecutive women undergoing oocyte retrieval were recruited. They un...

journal_title：Gynecologic and obstetric investigation

authors： Ragni G,Scarduelli C,Calanna G,Santi G,Benaglia L,Somigliana E

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND/AIMS:To evaluate patient satisfaction after laparoscopic supracervical (LASH) or total hysterectomy (TLH). METHODS:Retrospective study of patient satisfaction after LASH or TLH. RESULTS:We studied 40 cases of LASH and another 40 of TLH. The age of the patients, marital status, education level and employmen...

journal_title：Gynecologic and obstetric investigation

authors： Kafy S,Al-Sannan B,Kabli N,Tulandi T

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Genetic factors may play a role in male infertility. METHODS:In a prospective case-control study, we assessed the allele and genotype frequencies of the TNFalpha -308 C-->T and -863 C-->A polymorphisms, detected by PCR of sperm DNA, of 577 Caucasian men recruited in an infertility clinic. Semen sampling was...

journal_title：Gynecologic and obstetric investigation

authors： Kurz C,Bentz EK,Denschlag D,Berner I,Keck C,Tempfer CB,Pietrowski D

更新日期：2008-01-01 00:00:00

abstract：:Women with Kartagener's syndrome (KS) are at a risk for infertility because of the dyskinetic ciliary activity in the fallopian tubes. In vitro fertilization - embryo transfer (IVF-ET) is considered the treatment of choice for patients with tubal factor infertility. In the literature only 2 patients with KS were treat...

journal_title：Gynecologic and obstetric investigation

authors： Abu-Musa A,Nassar A,Usta I

更新日期：2008-01-01 00:00:00

abstract：INTRODUCTION:Scar deciduosis provides a research model that enables us to assess the impact of decidua on the activity and quality of the immune cells infiltrating this scar tissue. This unique model allows us to examine these processes under conditions excluding the impact of placental cells which, along with decidual...

journal_title：Gynecologic and obstetric investigation

authors： Skret-Magierlo J,Wicherek L,Basta P,Galazka K,Sikora J,Wilk M,Fudali L,Skret A

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Cervical hydatidiform molar pregnancy is an exceedingly rare occurrence that has been reported only twice before. CASE:We report a 25-year-old, G4P1D&C2 woman with a positive pregnancy test and vaginal bleeding. A cervical pregnancy with hydatidiform mole was detected on transvaginal ultrasound and color Do...

journal_title：Gynecologic and obstetric investigation

authors： Aytan H,Caliskan AC,Demirturk F,Koseoglu RD,Acu B

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND/AIMS:There is a lack of evidence in the literature supporting vaginal application of a combination hormone-containing cream for local and systemic symptom relief. This pilot study examined the extent of absorption of a single cream containing estriol, estradiol, progesterone, DHEA, and testosterone. METHODS...

journal_title：Gynecologic and obstetric investigation

authors： Glaser RL,Zava DT,Wurtzbacher D

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND/AIMS:Uterine leiomyomas are the most common gynecological benign tumor and greatly affect reproductive health and well-being. The pathophysiology and epidemiology of fibroids are poorly understood. Obesity and elevated blood pressure have been reported to be predisposing factors. In this study, we investigat...

journal_title：Gynecologic and obstetric investigation

authors： Takeda T,Sakata M,Isobe A,Miyake A,Nishimoto F,Ota Y,Kamiura S,Kimura T

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVE:Qinba Mountain area of Shanxi Province, China, is one of the poorest, culturally backward regions in China with a high incidence of mental retardation. To investigate whether cytomegalovirus (CMV) plays a role in the high incidence of mental retardation in this region, we studied the incidence of CMV infectio...

journal_title：Gynecologic and obstetric investigation

authors： Zhang JP,Li F,Yu XW,Sheng Q,Shi XW,Zhang XW

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Angioleiomyoma (ALM) is a rare, benign neoplasm involving the peripheral soft tissues. ALM has not previously been described to originate from the ovary. We present a case herein of a premenarchal girl with a large ALM originating from the ovary. CASE:An 11-year-old girl underwent a laparotomy during the co...

journal_title：Gynecologic and obstetric investigation

authors： Hsu TL,Changchien CC,Huang CC,Lin H

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:A hypoxic environment is known to be essential for early placentation. A low oxygen tension induces hypoxia-inducible factor-1 (HIF-1alpha) which may play an important role as a transcription factor in maintaining the proliferative and undifferentiated phenotype in human trophoblasts. METHODS:We analyzed th...

journal_title：Gynecologic and obstetric investigation

authors： Takeda T,Sakata M,Isobe A,Yamamoto T,Nishimoto F,Minekawa R,Okamoto Y,Tasaka K,Murata Y

更新日期：2007-01-01 00:00:00

abstract：AIM:We report a case of a mixed clear cell and endometrioid carcinoma arising in parietal endometriosis. METHODS:A 46-year-old woman presented a second recurrence of parietal endometriosis. An extensive surgical resection of the tumor was then carried out. RESULTS:Histological analysis revealed heterogeneous tissues ...

journal_title：Gynecologic and obstetric investigation

authors： Razzouk K,Roman H,Chanavaz-Lacheray I,Scotté M,Verspyck E,Marpeau L

更新日期：2007-01-01 00:00:00

abstract：:We focus on the roles of decidual and cumulus oophorus T cells. It was suggested that Th1-type cytokines (IFN-gamma and TNF-beta), which promote allograft rejection, may compromise pregnancy, whereas the Th2-type cytokines (IL-4, IL-5, IL-10) inhibiting the Th1 responses promote allograft tolerance and therefore may i...

journal_title：Gynecologic and obstetric investigation

authors： Piccinni MP

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:To evaluate whether prolactin, alpha-fetoprotein (AFP) or B-human chorionic gonadotropin (BHCG) is the most effective marker in vaginal fluid for diagnosing prelabor rupture of membranes (PROM). These proteins are present in amniotic and vaginal fluid and have been reported to be potent markers of PROM, but h...

journal_title：Gynecologic and obstetric investigation

authors： Shahin M,Raslan H

更新日期：2007-01-01 00:00:00

abstract：AIMS:The objective of this study was to determine whether the maternal surface of the placenta is fractal, and whether the mean fractal dimension differs according to the gestational age and clinically or pathologically different conditions. METHODS:Using digitized images of the maternal surface of 75 placentas, fract...

journal_title：Gynecologic and obstetric investigation

authors： Shiba M,Kikuchi A,Hara K,Sunagawa S,Yoshida S,Takagi K,Ogiso Y

更新日期：2007-01-01 00:00:00